Can I use a boot hard drive with different computers?

If you have Windows 10 installed, there is a good chance that your drive will just work^TM with another set of hardware.

You can install all drivers that both systems might need. That being said, conflicting drivers might cause unstable system performance. Boot up your system in your new hardware configuration and test it out.

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On a side note, Windows 10 is known to have licensing issues when there is too much hardware change in your system. You might end up losing your license for Windows 10.

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