OWA wont work with Chrome?

Everything was working just fine before. Suddenly OWA stopped working with Chrome in my company, there was no change made to domain and GPO. On chrome, it shows login page, once logged in, it becomes a blank page....

Any idea what could be the cause.

Chrome: Version 51.0.2704.84 m

Exchange 2013

OWA from anywhere enabled

HTTPS enabled