USB Issues - Mobo or jack/cable?

On a machine I built I'm getting some odd behavior on the case USB jacks. I hook up a wireless keyboard and mouse and every now-and-then (every 3 min or so usually) the keyboard will type extra strokes. Mouse doesn't jump around. Now I've fried two flash drives on those jacks as well - they won't read on other computers after being on this one for a bit.

I replaced the keyboard/mouse and tested the old on another computer. I'm fairly certain the issue is related to these front USB jacks. How can I test whether the issue is the jack/cable or the mobo?

Thank you.

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